Science + Innovation
Novel target underpinned by 15+ years of scientific research and innovation.
Our Focus
Vandria has identified a novel metabolic target that plays a key role regulating energy production within cells, enhancing overall efficiency. The target has strong genetic links to several human diseases, especially neurodegenerative diseases.
With a focus on halting or slowing the progression of age-related diseases, we are developing first-in-class small molecule innovative therapeutics that restore mitochondrial function and reduce chronic inflammation to treat age-related-diseases.
About Age-Related Diseases
Mode of Action
Vandria’s New Chemical Entities (NCEs) have been shown to modulate a key metabolic target (Target A) in the cytosol that restores the oxidative phosphorylation pathway in mitochondrial respiration. This, in turn, induces autophagy and mitophagy, reduces protein aggregation and protects against cell death. It also has the additional effect of reducing the release of proinflammatory cytokines.
